南方科技大学是由中国广东省领导和管理、深圳市举全市之力创建的一所公办创新型大学,目标是迅速建成国际化高水平研究型大学,建成中国重大科学技术研究与拔尖创新人才培养的重要基地……

南方科技大学以学分制、导师制、书院制为基础,以人才培养的个性化、小班化、国际化为特色,通过为一流的人才培养体系,培养人格健全、基础扎实、能力突出、具有国际视野、社会责任感、创新精神和实践能力的高素质人才。

南方科技大学被确定为国家高等教育综合改革试验校。2012年4月,教育部同意建校,并赋予学校探索具有中国特色的现代大学制度、探索创新人才培养模式的重大使命。

南方科技大学对本科学生采用书院制管理模式,以书院、团委、社团等平台为载体,为学生营造了精彩的大学生活。

南方科技大学本科招生采用基于高考的综合评价录取模式,即高考成绩占60%,我校自主组织的能力测试成绩占30%(其中面谈成绩为5%),高中学业水平考试成绩占10%,按考生“631”综合成绩排名从高到低录取。综合评价录取模式由我校在2012年率先实施。

南科大教育基金会由理事会、监事会、秘书处组成。理事会是基金会的最高权力机构;监事会负责检查财务和会计资料,监督理事会遵守法律和章程的情况;秘书处是基金会常设办事机构,在理事会领导下负责基金会的日常工作。

学校党委切实履行党建工作职责,不断强化班子建设和基层党组织建设,充分发挥好党委对学校各项工作的核心统领作用和各党支部的战斗堡垒作用,切实开展组织统战和党风廉政建设各项工作。学校高度重视群团组织建设,充分调动全体师生员工积极性,维护教职工的合法权益,推进学校民主管理,促进学校健康发展,全力营造齐心协力、团结向上、奋发有为的干事创业氛围。

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首页 > 师资队伍 > 全部教师列表A-Z > 何安竹(Andrew Hutchins)

师资队伍

何安竹(Andrew Hutchins)


助理教授

生物系

andrewh@sustc.edu.cn

自我介绍:

研究项目属于实验科学和计算科学的交叉领域。通过新一代测序技术深入、全面、系统地了解细胞生物学、表观遗传学和人类疾病的各个方面。

 

个人经历:
2013-2015, Associate Investigator and Project Research Scientist, Guangzhou Institutes of Biomedicine and Health, China
2010-2013, Associate Investigator. Immunology Frontier Research Centre, Osaka University, Japan
2004-2010, Postdoctoral Fellow, Genome Institute of Singapore, Singapore


教育背景:
2004, PhD, John Innes Centre, and University of East Anglia, Norwich, UK.
2000, BSc, University of Wolverhampton, UK.
 
代表文章:
https://scholar.google.com/citations?user=ckL_UUQAAAAJ&hl=en
1.Ying Z, Chen K, Zheng L, Wu Y, Li L, Wang R, Long Q, Yang L, Guo J, Yao D, Li Y, Bao F, Xiang G, Liu J, Huang Q, Wu Z, Hutchins AP, Pei D, Liu X (2015) Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming. Cell Metabolism. S1550-4131(15)00518-5
2.Hutchins AP#, Pei D#, (2015) Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming and long non-coding RNAs. Scientific Bulletin. 60(20):1722-1733. #Co-corresponding authors.
3.Hutchins AP#, Robson P# (2015) Transcriptional Intricacies of Stem Cells. Cell Systems. 1(2); 100-101. #Co-corresponding authors.
4.Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Lin G, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. (2015) The oncogene c-Jun impedes somatic reprogramming. Nature Cell Biology. 17(7):856-67.
5.Hatzihristidis T, Desai N, Hutchins AP, Meng T, Tremblay ML, Miranda-Saavedra D. (2015) A Drosophila-centric view of protein tyrosine phosphatases. FEBS Letters. 589(9):951-966.
6.Hutchins AP#, Takahashi Y, Miranda-Saavedra D#. (2015) Genomic analysis of LPS-stimulated myeloid cells indicates a common pro-inflammatory response but divergent IL-10 anti-inflammatory responses. Scientific Reports. 5:9100. #Co-corresponding authors.
7.Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K, Yin M, Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Pei D, Wang H, Zhang B, Esteban MA. (2015) The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters. Cell Research. 25(1):80-92.
8.Pike KA*, Hutchins AP*, Vinette V, Theberge J, Sabbagh L, Tremblay M, Miranda-Saavedra D. (2014) Protein tyrosine phosphatase-1B is a regulator of the IL-10 induced transcriptional program in macrophages. Science Signaling. 6;7(324)ra43. *As co first authors.
9.Hutchins AP#, Dyla M, Jauch R, Miranda-Saavedra D. (2014) glbase: a framework for combining, analyzing and displaying heterogeneous genomic and high-throughput sequencing data. Cell Regeneration. 3(1):1. #Corresponding author.
10.Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. (2014) Transcriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming. Cell Stem Cell. 15(5):574-88.
11.Zheng H, Hutchins AP, Pan G, Li Y, Pei D, Pei G. (2014) Where cell fate conversions meet Chinese philosophy. Cell Research. 24(10):1162-3.
12.Diez D, Hutchins AP, Miranda-Saavedra D. (2014) Systematic identification of transcriptional regulatory modules from protein-protein interaction networks. Nucleic Acids Research. 42(1); e6.
13.Bussières-Marmen S, Hutchins AP, Schirbel A, Rebert N, Tiganis T, Fiocchi C, Miranda-Saavedra D, Tremblay ML. (2014) Characterization of PTPN2 and its use as a biomarker. Methods. 65(2);239-46.
14.Hatzihristidis T, Liu S, Pryszcz L, Hutchins AP, Gabaldon T, Tremblay ML, Miranda-Saavedra D. (2014)  PTP-central: A Comprehensive Resource of Protein Tyrosine Phosphatases in Eukaryotic Genomes. Methods. 65(2);156-64.
15.Hutchins AP#, Choo SW, Mistri TK, Rahmani M, Woon CT, Ng CKL, Jauch R, Robson P#. (2013) Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells. Stem Cells. 31(2):269-281. #Co-corresponding authors.
16.Aksoy I*, Jauch R*, Chen J, Dyla M, Divakar U, Bogu GK, Ng CKL, Herath W, Hutchins AP, Robson P, Kolatkar PR, Stanton LW. (2013) Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm. EMBO Journal. 32(7);938-953. *As co-first authors.
17.Clarke M, Lohan AJ, et al., … Hutchins AP, … Miranda-Saavedra D, … Loftus B. (40 authors in total) (2013) Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of pattern recognition and tyrosine kinase signalling. Genome Biology. 14(2):R11.
18.Hutchins AP, Diez D, Miranda-Saavedra D. (2013) The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges. Briefings in Functional Genomics. 12(6);489-98.
19.Hutchins AP, Diez D, Miranda-Saavedra D. (2013) Genomic and computational approaches to dissect the mechanisms of STAT3’s universal and cell-type-specific functions. JAK-STAT. 2(4);e25097
20.Hutchins AP*, Liu S*, Diez D. Miranda-Saavedra D. (2013) The repertoires of ubiquitinating and deubiquitinating enzymes in eukaryotic genomes. Molecular Biology and Evolution. 30(5);1172-1187. *As co-first authors.
21.Hutchins AP, Diez D, Takahashi Y, Ahmad S, Jauch R, Tremblay M, Miranda-Saavedra D. (2013) Distinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions. Nucleic Acids Research. 41(4):2155-2170.
22.Hutchins AP, Poulain S, Fujii H, Miranda-Saavedra D. (2012) Discovery and characterization of new transcripts from RNA-seq data in mouse CD4+ T cells. Genomics. 100(5):303-313.
23.Hutchins AP, Poulain S, Miranda-Saavedra D. (2012) Genome-wide analysis of STAT3 binding in vivo predicts effectors of the anti-inflammatory response in macrophages. Blood. 119(13):e110-e119.
24.Jauch R*, Aksoy I*, Hutchins AP*, Ng CK, Tian XF, Chen J, Palasingam P, Robson P, Stanton LW, Kolatkar PR. (2011) Conversion of Sox17 into a Pluripotency Reprogramming Factor by Re-engineering its Association with Oct4 on DNA. Stem Cells. 29(6):940-951. *As co-first authors.
25.Hutchins AP, Robson P. (2009) Unraveling the Human Embryonic Stem Cell Phosphoproteome. Cell Stem Cell. 5(2):126-128.
26.Bush MS, Hutchins AP, Jones AME, Naldrett MJ, Jarmolowski A, Browning K, Lloyd CW, Doonan JH. (2009) Selective recruitment of proteins to 5' cap complexes during the growth cycle in Arabidopsis. Plant Journal. 59(3):400-412.
27.Hutchins AP, Roberts GR, Lloyd CW, Doonan JH. (2004) In vivo interaction between CDKA and eIF4A: a possible mechanism linking translation and cell proliferation. FEBS Letters. 556(1-3):91-94.

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