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ZHANG zhiqian

Research Assistant Professor

School of Medicine

Room 502, Building B

Work Experience

A. 3.2012-6.2014: Visiting student, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
B. 7.2014-7.2015: Postdoctoral Fellow, MD Anderson Cancer Center, Houston, Texas, USA.

C. 7.2015-4.2017: Assistant Investigator, State Key Laboratory of pharmaceutical chemistry and biology, Nankai University.
D. 5.2017-10.2018: Tianjin Come Biotechnology Co., Ltd, Vice president, Executive director, Technical Director.

E. 11.2018 – Present, Research Assistant Professor, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China


A. 9.2004-6.2008: B.Sc. in Biology, Nankai University, Tianjin, China.
B. 9.2008-6.2014: Ph.D. in Genetics, Nankai University, Tianjin, China.


Selected publications
1. Tao, F., Tian, X., Ruan, S., Shen, M. and Zhang, Z. miR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma. FASEB JOURNAL 2018; fj201800495RR. (Corresponding author)
2. Tao F, Tian X, Lu M and Zhang Z. A novel lncRNA, Lnc-OC1, promotes ovarian cancer cell proliferation and migration by sponging miR-34a and miR-34c. J Genet Genomics 2018; 45: 137-145.(Corresponding author)
3. Tao, F., Tian, X., and Zhang, Z. (2018) The PCAT3/PCAT9-miR-203-SNAI2 axis functions as a key mediator for prostate tumor growth and progression. Oncotarget 9, 12212-12225 (Corresponding author)
4. Tian, X., Tao, F., Zhang, B., Dong, J. T., and Zhang, Z. (2018) The miR-203/SNAI2 axis regulates prostate tumor growth, migration, angiogenesis and stemness potentially by modulating GSK-3beta/beta-CATENIN signal pathway. IUBMB Life 70, 224-236 (Corresponding author)
5. Tian, X., and Zhang, Z. (2018) miR-191/DAB2 axis regulates the tumorigenicity of estrogen receptor-positive breast cancer. IUBMB Life 70, 71-80(Corresponding author)
6. Zhang, Z., Zhu, Z., Zhang, B., Li, W., Li, X., Wu, X., Wang, L., Fu, L., Fu, L., and Dong, J. T. (2014) Frequent mutation of rs13281615 and its association with PVT1 expression and cell proliferation in breast cancer. J Genet Genomics 41, 187-195 (First Author)
7. Zhang, Z., Zhang, B., Li, W., Fu, L., Fu, L., Zhu, Z., and Dong, J. T. (2011) Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells. Genes Cancer 2, 782-791 (First Author)
8. Huang, Y.#, Qi, H.#, Zhang, Z.#, Wang, E.#, Yun, H., Yan, H., Su, X., Liu, Y., Tang, Z., Gao, Y., Shang, W., Zhou, J., Wang, T., Che, Y., Zhang, Y., and Yang, R. (2017) Gut REG3gamma-Associated Lactobacillus Induces Anti-inflammatory Macrophages to Maintain Adipose Tissue Homeostasis. Front Immunol 8, 1063 (Co-first author)
9. Xin, J.#, Zhang, Z.#, Su, X., Wang, L., Zhang, Y., and Yang, R. (2017) Epigenetic Component p66a Modulates Myeloid-Derived Suppressor Cells by Modifying STAT3. J Immunol 198, 2712-2720 (Co-first author)
10. Ruan, S. #, Zhang, Z. #, Tian, X. #, Huang, D. #, Liu, W., Yang, B., Shen, M., Tao, F. (2018) Compound Fuling Granule Suppresses Ovarian Cancer Development and Progression by disrupting mitochondrial function, galactose and fatty acid metabolism. J Cancer. 9(18):3382-3393 (Co-first author)
11. Zhang, Z., Zhu, Z., Zhang, B. & Dong, J.T. Epigenetic regulation of miRNAs in breast cancer formation and progression. In: F. H. Sarkar (ed.) Epigenetics and cancer, pp. 95-114. New York: Springer, 2013(Chapter)

Research Fields

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