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Yu Cong

Associate Professor

Department of Biology



Dr.Yu’s research work mainly focus on the structural and functional studies of the proteins involved in cell-ECM adhesion, intracellular trafficking and many neuronal diseases, by combining the powerful tools in biochemistry, biophysics and cell biology. The research results have been published on Cell, Molecular Cell etc, and Dr.Yu has been awarded Hong Kong Young Scientist Award in Life Science (2009), and the Peacock Plan (2014, Shenzhen)


Professional Experience:

◆ Aug. 2013-present  Associate Professor, South University of Science and Technology of China

◆ Sep. 2009 – Aug. 2013 Research Associate in Division of Life Science, the Hong Kong University of Science and Technology


Educational Background:

◆ Jan. 2004 –Aug. 2009 Ph.D., Biochemistry, the Hong Kong University of Science and Technology

◆ Sep. 1998 – Jun.2003 B.S., Biology, University of Science and Technology of China


Honors & Awards:

◆Hong Kong Young Scientist Award in Life Science, Hong Kong Institute of Science 2009

◆Postgraduate Achievement Award, Biochemistry, Hong Kong University of Science and Technology 2009

◆Postgraduate Student Research Award, Biochemistry,Hong Kong University of Science and Technology 2009


Selected Publication:

◆Yu,C.*, Lou,J.*, Wu,J., Pan,L., Feng,W., and Zhang,M. (2012) . Membrane-induced lever arm expansion allows myosin VI to walk with large and variable step sizes. J Biol Chem 287(42),35021-35.  doi: 10.1074/jbc.M111.328781 (*: co-first authors)

◆Wei, Z., Zheng, S., Spangler, S.A., Yu, C.#, Hoogenraad, C.C., Zhang, M. # (2011) . Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures.  Mol Cell 43:586-98.  doi: 10.1016/j.molcel.2011.07.021.  (#: co-correspondence authors)

◆Yu, C.*, Feng, W.*, Wei, Z., Miyanoiri, Y., Wen, W., Zhao, Y., and Zhang, M. (2009). Myosin VI Undergoes Cargo-Mediated Dimerization.  Cell 138, 537-548. doi: 10.1016/j.cell.2009.05.030. (*: co-first authors)

◆Wang C, Wei Z, Chen K, Ye F, Yu C, Bennett V, Zhang M. (2014). Structural basis of diverse membrane target recognitions by ankyrins.  Elife.  Nov 10;3.

◆Wei, Z., Liu, X., Yu, C., Zhang, M. (2013). Structural basis of cargo recognitions for class V myosins. Proc Natl Acad Sci U S A. 110(28),11314-9. doi: 10.1073/pnas.1306768110

◆Wang, C., Yu, C., Ye, F., Wei, Z., Zhang, M. (2012) Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function. Proc Natl Acad Sci U S A. 109(13),4822-7. doi: 10.1073/pnas.1200613109. 

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