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Song Xuejun




Xue-Jun Song, MD, PhD, Professor of Neuroscience, Anesthesiology and Pain Medicine, has been serving at SUSTC since 2016. Dr. Song’s research has focused on basic science research of neurobiology of neuropathic/cancer pain and general anesthesia as well as on cancer pain management strategies. These efforts have resulted in several dozens of original research articles in peer-reviewed journals including Anesthesiology, Brain, Cancer Res, JCI, J Neurosci, Nat Neurosci, Pain, etc., as well as in invention patents. Many of his research outcomes were highlighted, reviewed, or reported by major scientific organizations and journals including Nature Review Drug Discovery, Nature Publishing Group, PainResForum, American Association of Cancer Research, American Physiological Society, International Association for the Study of Pain (IASP), and key international media like NBC, CBS, etc. Dr. Song has received research fund from PRF, NIH, DOD, NSFC, and other foundations from USA, Australia and China. Dr. Song is currently President of the China Chapter of IASP, Vice Chair of Translational Pain Research Committee of Chinese Physiological Society, a member of the Standing Committee of Chinese Anesthesia-Pharmacological Society, Vice Secretary General of Chinese Pain Medical Association, and a member of the Standing Committee of International Chinese Academy of Anesthesiology, and also serves as editor-in-chief of the Chinese version of the journal PAIN.


Professional Experience:
2016—         Professor of Neurobiology, Anesthesiology and Pain Medicine, Department of Biology, SUSTC; Member of Planning Committee, SUSTC Medical School
2013—2016  Co-Founder, Executive Director, and Vice Chair of its Academic Advisory Committee, Center for Pain Medicine, Peking University Health Science Center
2012—2016  Professor of Neurobiology and Pain Medicine, and Director of Laboratory of Pain Plasticity, Neuroscience Research Institute and Department of Neurobiology, Peking University
2004—2016  Professor of Neurobiology and Pain Medicine, Member of Academic Advisory Committee, Parker University, Dallas, Texas, USA
2000—2016  Associate Director of Parker Research Institute, Director of Section of Basic Science Research, Parker University
1999—2003  Assistant and then Associate Professor, Parker University
1998—1999  Instructor and then Research Assistant Professor, The University of Texas Medical Center, Houston, Texas, USA
1995—1998  Postdoctoral Fellow, Department of Anesthesiology and Section of Neurobiology, Yale University, New Haven, CT, USA
1986—1995  Zhujiao/Lecturer/Associate Professor, Department of Physiology and Department of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, China.   
2006—2013  Adjunct Professor, Institute of Neuroscience and Department of Anesthesiology, The Fourth Military Medical University, Xi’an, China 
2005—2010  Distinguished Professor of Anesthesiology, Director of Jiangsu Province Key Lab of Anesthesiology, Vice Dean of College of Anesthesiology, and Director of Center for Pain Research and Management, Xuzhou Medical University

Educational Background:
1981-1986  MD in Medicine, Xuzhou Medical University
1989-1992  MS in Anesthesiology, Xuzhou Medical University
1990-1995  PhD in Neurobiology, Institute of Neuroscience, Chinese Academy of Sciences

Honors & Awards:
2015  The Louis Sportelli NCMIC Award, WFC, Athens, Greece 
2014  Distinguished Medical Expert, Jiangsu Province Government, China 
2006  Extraordinary Young Scientist Award, National Nature Science Foundation of China
2004  The Scott Haledeman Award, WFC, Sydney, Australia
2005  Outstanding Professorship Award, Parker University
2005  Researcher of the Year, Activator International LTD, USA   
2004  Award of Advancement of Science and Technology (first class), Ministry of Education
1999  Award of Natural Science (second class), Chinese Academy of Sciences
1995  Outstanding Young Scientist Award, Chinese Academy of Sciences Shanghai Branch
1994  Presidential Award, Chinese Academy of Sciences 
1993  Research Award for National Young Scientists (second class), Zhang Xijun Foundation,  Chinese Physiological Society

Selected Recent Publications:
1.    Xu N, Wu MZ, Deng XT, Ma PC, Li ZH, Liang L, Song XJ. Inhibition of YAP/TAZ Activity in Spinal Cord Suppresses Neuropathic Pain. J Neurosci (2016, in press).
2.    Liu S, Liu YP, Huang ZJ, Zhang YK, Song AA, Ma PC, Song XJ. Wnt/Ryk signaling contributes to neuropathic pain by regulating sensory neuron excitability and spinal synaptic plasticity in rats. Pain 2015; 156(12):2572-84.
3.    Zhang YK, Huang ZJ, Liu S, Liu YP, Song AA, Song XJ. WNT signaling underlies the pathogenesis of neuropathic pain in rodents. J Clin Invest 2013; 123(5):2268-86. 
4.    Liu S, Liu YP, Song WB, Song XJ. EphrinB-EphB receptor signaling contributes to bone cancer pain via Toll-like receptor and proinflammatory cytokines in rat spinal cord. Pain 2013;154(12):2823-35.
5.    Huang ZJ, Li HC, Cowan AA, Zhang YK, Song XJ. Chronic compression or acute dissociation of dorsal root ganglion induces cAMP-dependent neuronal hyperexcitability through activation of PAR2. Pain 2012, 153:1426-1437. 
6.    Wu XF, Liu WT, Liu YP, Huang ZJ, Zhang YK, Song XJ. Reopening of ATP-sensitive potassium channels reduces neuropathic pain and regulates astroglial gap junctions in the rat spinal cord. Pain 2011; 152:2605-2613.
7.    Liu S, Liu WT, Liu YP, Dong HL, Henkemeyer M, Song XJ. Blocking EphB1 receptor forward signaling in spinal cord relieves bone cancer pain and rescues analgesic effect of morphine treatment in rodents. Cancer Research 2011;71(13):4392-402.
8.    Liu WT, Han Y, Liu YP, Song AA, Barnes B, Song XJ. Spinal matrix metalloproteinase-9 contributes to physical dependence on morphine in mice. J Neurosci, 2010; 30: 7613-7623.
9.    Liu WT, Li HC, Song XS, Huang ZJ, Song XJ. EphB receptor signaling in mouse spinal cord contributes to physical dependence on morphine. FASEB J 2009; 23(1):90-98. 
10.    Song XS, Huang ZJ, Song XJ. Thiamine may suppress thermal hyperalgesia by inhibiting hyperexcitability and regulating altered sodium channel of the injured dorsal root ganglion neurons in rats. Anesthesiology 2009; 110:387-400.



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