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Faculty

Chen Fangyi


Associate Professor

Department of Biomedical Engineering

chenfy@sustc.edu.cn

Education:

PhD (Jan 2005) in Electrical Engineering Boston University, Boston, MA 

Dissertation: A Hydro-mechanical Biomimetic Cochlea: Experiments and Models 

MS (July 2000) in Biomedical Engineering, Tsinghua University, Beijing, China 

BS (July 1997) in Biomedical Engineering, Tsinghua University, Beijing, China 

 

Work experiences:

2012.9 – present Associate Professor, South University of Science and Technology of China

2009. 5 – 2012.9 Research Associate/ Engineer, Oregon Health and Science University 

2008. 7 – 2009. 3 Senior System Design Engineer, KLA-Tencor corp. CA 

2006. 7 – 2008. 7 Research Associate/ Engineer, Oregon Health and Science University 

2004.12 – 2006. 7 Postdoctoral research fellow. Oregon Health and Science University 

 

Major Awards :
2012           The Recruitment Program of Global Youth Experts, China central government
2005-2006: Postdoctoral Fellow, Cochlear Mechanics Lab, Oregon Hearing Research Center 
2003:      Dean’s Award for the best Poster in Science and Technology Day, Boston University 
2000-2001: Dean’s Fellowship, College of Engineering, Boston University 

 

 

Journal publications:

Ramamoorthy S, Zha D, Chen F, Jacques SL, Wang R, Choudhury N, Nuttall AL, Fridberger A. “Filtering of acoustic signals within the hearing organ. ” J Neurosci. 2014 Jul 2;34(27):9051-8. doi: 10.1523/JNEUROSCI.0722-14.2014. (equally contributed)
Subhash HM, Choudhury N, Chen F, Wang RK, Jacques SL, Nuttall AL. “Depth-resolved dual-beamlet vibrometry based on Fourier domain low coherence interferometry.”J Biomed Opt. 2013;18(3):036003.
Zha D, Chen F*, Ramamoorthy S, Fridberger A, Choudhury N, et al. (2012) In Vivo Outer Hair Cell Length Changes Expose the Active Process in the Cochlea. PLoS ONE 7(4) (Corresponding author)
Chen F, Zha D, Fridberger A, Zheng J, Choudhury N, Jacques SL, Wang RK, Shi X, Nuttall AL.  2011 A differentially amplified motion in the ear for near-threshold sound detection, Nat Neurosci. June 2011. v14: 770-775 
Zheng J, Ramamoorthy S, Ren T, He W, Zha D, Chen F, Magnusson A, Nuttall AL, Fridberger A. “Persistence of past stimulations: storing sounds within the inner ear.” Biophys J. 2011 Apr 6;100(7):1627-34.
Mo W., Chen F., Nechiporuk A. and Nicolson T. “Quantification of vestibular-induced eye movements in zebrafish larvae”  BMC Neuroscience 2010, 11:110 (equally contributed)
Choudhury, N., Chen, F., Zheng, J., Nuttall, A.L., and Wang, R.K. “Volumetric imaging of blood flow within cochlea in gerbil in vivo.” IEEE J Sel Top Quantum Electron. 2009 Oct 20;PP(99):1-6.
Chen, F. and Nuttall, A. “Comment on “Measuring power production in the mammalian cochlea” [Curr. Biol. 17, 1340 (2007)] (L)” Journal of Acoustic Society of America Volume 125, Issue 1, pp. 11-14 (2009) 
Chen, F., Choudhury, N., Zheng, J., Matthews, S., Nuttall, A. and Jacques, S., “In vivo imaging and low-coherence interferometry of cochlear membrane vibration” Journal of Biomedical Optics. Volume 12, Issue 2. This paper was selected into April 15, 2007 issue of “Virtual Journal of Biological Physics Research”, an on-line collection of papers in biological physics research. 
Chen, F., Cohen, H., Kapusta, C., Fortin, J., Bifano, T., Mountain, D., Zosuls, A., and Hubbard, A “A hydro-mechanical biomimetic cochlea: Experiments and models” Journal of Acoustic Society of America Volume 119,  Issue 1, pp. 394-405. This paper was selected into January 15, 2006 issue of “Virtual Journal of Biological Physics Research”, an on-line collection of papers in biological physics research. 
Choudhury, N., Song, G., Chen, F., Matthews, S., Tschinkel, T., Zheng, J., Jacques, S., and Nuttall, A.L. “Low  coherence interferometry of cochlear partition,” Hear. Res. 220(1,2), 1–9 (2006). 
Fangyi Chen, Tao Wu, Teresa Wilson, Hrebesh Subhash, Irina Omelchenko, Michael Bateschell, Lingyan Wang, John Brigande, Zhi-Gen Jiang, Alfred Nuttall “Expression and function of channelrhodopsin 2 in mouse outer hair cells”Proc. SPIE. 8586, Optogenetics: Optical Methods for Cellular Control 85860I (March 8, 2013) 
Sripriya Ramamoorthy, Yuan Zhang, Tracy Petrie, Fangyi Chen, Hrebesh M. Subhash, Niloy Choudhury, Ruikang Wang, Steven L. Jacques, Alfred L. Nuttall “Measurement of in vivo basal-turn vibrations of the organ of Corti using phase-sensitive Fourier domain optical coherence tomography“ Proc. SPIE. 8565, Photonic Therapeutics and Diagnostics IX 85651V (March 8, 2013) doi: 10.1117/12.2009260
Hrebesh M. Subhash, Ruikang K. Wang, Fangyi Chen, Alfred L. Nuttall "Reflective type objective based spectral-domain phase-sensitive optical coherence tomography for high-sensitive structural and functional imaging of cochlear microstructures through intact bone of an excised guinea pig cochlea" Proc. SPIE. 8571: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII  (March 8, 2013)
Fangyi Chen, Dingjun Zha, Anders Fridberger, Jiefu Zheng, Niloy Choudhury, Steven L. Jacques, Ruikang K. Wang, Alfred L. Nuttall “In vivo measurement of differential motion inside the organ of Corti using a low coherence interferometer system”  Proc. SPIE, Vol. 8207 (2012)
Hrebesh M. Subhash, Niloy Choudhury, Steven L. Jacques, Ruikang K. Wang, Fangyi Chen, Dingjun Zha, Alfred L. Nuttall “Absolute measurement of subnanometer scale vibration of cochlear partition of an excised guinea pig cochlea using spectral-domain phase-sensitive optical coherence tomography”  Proc. SPIE, Vol 8213 (2012)
Choudhury, N., Yaguang Zeng, Anders Fridberger, Chen, F., Dingjun Zha, Nuttall, A.L., and Ruikang K. Wang  “Imaging vibration of the cochlear partition of an excised guinea pig cochlea using phase-sensitive Fourier domain optical coherence tomography”  Proc. SPIE, Vol. 7889 (2011);
Chen, F., Zheng, J., Choudhury, N., Jacques, S., and Nuttall, A.L “Organ of Corti micromechanics with local electrical stimulation” In: Concepts and Challenges in the Biophysics of Hearing, Cooper N. and Kemp D. (ed),  Singapore: World Scientific Pr. 2009.
Choudhury, N., Chen, F., Zheng, J., Nuttall, A.L., and Jacques S. “In vivo imaging and vibration measurement of Guinea pig cochlea”  Proc. SPIE, Vol. 6847, 68471V (2008);
Chen, F., Cohen, H. I., Mountain, D., and Hubbard, A., “A hydro-mechanical biomimetic cochlea: experiments and models,” In: Auditory Mechanisms: Processes and Models, Nuttall AF et. al, (ed), Singapore: World Scientific Pr. 2006. 
Choudhury, N., Jacques S., Mathew S., Chen, F., Zheng, J., and Nuttall, A.L., “Low Coherence intereferometry of the cochlear partition,” In: Auditory Mechanisms: Processes and Models, Nuttall AF et. al, (ed), Singapore: World Scientific Pr. 2006. 
Hubbard A, Mountain D., Chen F., “Time-domain responses from a nonlinear sandwich model of the cochlea”, In: Biophysics of the Cochlea: From Molecule to model, Gummer AW (ed), Singapore: World Scientific Pr. 2002. 

 

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