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CHE Chi-Ming


Long-term Visiting Professor

Department of Chemistry

Prof. Che Chi-Ming, born in 1957, is an academician of Chinese Academy of Sciences (CAS). He was the first scientist in Hong Kong and Macao to win this honor. He is also a Foreign Associate of National Academy of Sciences(USA), an academician of the Third World Academy of Sciences(TWAS), a Fellow of the Royal Society of Chemistry (FRSC), a member of the World Foundation for Innovation, and a fellow of Federation of Asian Chemical Societies(FACS).. In 2006, he won the first-class prize of the National Natural Science Award. He is an editorial board member of such renowned magazines as Chemistry—A European Journal, Chemistry—An Asian Journal and Trends in Inorganic Chemistry. He was invited to serve as a Guest-Chair Professor in Peking University, Nanjing University, Fudan University, Jilin University, Sichuan University, Beijing Institute of Chemistry of CAS, Shanghai Institute of Organic Chemistry of CAS, and other research institutions.

 

Research Interests:

◆ Inorganic and organic synthesis chemistry, multiple bonds of metal-ligand complexes chemical, metal-catalyzed organic reactions, inorganic photochemistry, light-emitting materials, bio-inorganic chemistry, and inorganic medicinal chemistry.

Professional Experience:

◆ Since 1992 Chair Professor The University of Hong Kong

◆ 1990-1992 Reader The University of Hong Kong

◆ 1983-1990 Lecturer The University of Hong Kong

Educational Background:

◆ 1980-1983 Postdoctoral Fellow California Institute of Technology

◆ 1978-1980 Ph.D. The University of Hong Kong

◆ 1975-1978 B.S. The University of Hong Kong

Honors & Awards:

◆ He is an academician of Chinese Academy of Sciences (CAS). He was the first scientist in Hong Kong and Macao to win this honor. He is also a Foreign Associate of National Academy of Sciences(USA), an academician of the Third World Academy of Sciences(TWAS), a Fellow of the Royal Society of Chemistry (FRSC), a member of the World Foundation for Innovation, and a fellow of Federation of Asian Chemical Societies(FACS).. In 2006, he won the first-class prize of the National Natural Science Award.

Selected publications:

◆ W. Lu, W.-M. Kwok, C. Ma, C. T.-L. Chan, M.-X. Zhu, C.-M. Che*. Organic triplet excited states of gold(I) complexes with oligo(o- or m-phenyleneethynylene) ligands: conjunction of steady-state and time-resolved spectroscopic studies on exciton delocalization and emission pathways. J. Am. Chem. Soc. 2011, 133, 14120–14135.

◆ Y. P. Xiao, X. Y. Liu, C.-M. Che* . Efficient gold(I)-catalyzed direct intramolecular hydroalkylation of unactivated alkenes with alpha-ketones. Angew. Chem. Int. Ed. 2011, 50, 4937–4941.

◆ C.-M. Che,* V. K. Y. Lo, C. Y. Zhou, J. S. Huang. Selective functionalisation of saturated C-H bonds with metalloporphyrin catalysts. Chem. Soc. Rev. 2011, 40, 1950–1975.

◆ T. W. S. Chow, E. L. M. Wong, Z. Guo, Y. G. Liu, J. S. Huang, C.-M. Che*. cis-Dihydroxylation of Alkenes with Oxone Catalyzed by Iron Complexes of a Macrocyclic Tetraaza Ligand and  Reaction Mechanism by ESI-MS Spectrometry and DFT Calculations. J. Am. Chem. Soc. 2010, 132, 13229–13239.

◆ C. T. Lum, X. Liu, R. W. Y. Sun, X. P. Li, Y. Peng, M. L. He, H. F. Kung, C.-M. Che,* M. C. M. Lin*.  Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro. Cancer Lett. 2010, 294, 159–166.

◆ C.-M. Che,* F. M. Siu . Metal complexes in medicine with a focus on enzyme inhibition. Curr. Opin. Chem. Biol. 2010, 14, 255–261.

◆ C. M. Ho,J. L. Zhang, C. Y. Chou, O. Y. Chan, J. J. Yan, F. Y. Zhang, J. S. Huang, C.-M. Che*. A water-soluble ruthenium glycosylated porphyrin catalyst for carbenoid transfer reactions in aqueous media with applications in bioconjugation reactions. J. Am. Chem. Soc. 2010, 132, 1886–1894.

◆ G. S. M. Tong, P. K. Chow, C.-M. Che* . Where is the heavy-atom effect? Role of the central ligand in tetragold(I) ethynyl complexes. Angew. Chem. Int. Ed. 2010, 49, 9206–9209.

◆ Y. Chen, K. Li, W. Lu,* S. S.-Y. Chui, C.-W. Ma, C.-M. Che* . Photo-responsive supramolecular organometallic nanosheets induced by PtII•••PtII and C–H•••π interactions. Angew. Chem. Int. Ed. 2009, 48, 9909–9913.

◆ X. Y. Liu, C.-M. Che* . Highly efficient and regioselective platinum(II)-catalyzed tandem synthesis of multiply substituted indolines and tetrahydroquinolines. Angew. Chem. Int. Ed. 2009, 48, 2367–2371.

Research & Grants:

Prof. Che Chi-Ming has devoted in the inorganic chemistry basic research for a long term, and made a series of achievements in the synthesis of inorganic and organic compounds, high-valence metal ligand multiple bonds, luminescent inorganic and organometallic compounds, photoinduced electron- and atom-transfer reaction, metal-catalyzed oxidation reactions, bioinorganic chemistry/inorganic medicinal chemistry, and phosphorescent materials. Prof. Che Chi-Ming was the first Hong Kong scientist to win the first-class prize since Hong Kong took part in the recommendation of the National Natural Science Award in 1989 with his project “Research on Reactivity of Multiple Bonds in Metal Complexes”. His research achievements made breakthrough progress in innovation and development and in highly efficient and green chemical reactions, and have significant impact on modern chemical industry, drug synthesis, and discovery of novel molecular materials. He has supervised more than 100 PhD students, and published over 800 articles in journals with high SCI Impact Factors like J. Am. Chem. Soc. and Angew. Chem. Int. Ed.. With his papers being cited over 28000 times and having a current h-index of 83, Prof. Che Chi-Ming is among the most-cited scientists in the world.

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